282 - Uses, Side Effects, Interactions - MedBroadcast.com (2024)

How does this medication work? What will it do for me?

This combination product contains three medications: acetylsalicylic acid (ASA), codeine, and caffeine.

ASA belongs to the group of medications called analgesics (pain relievers), anti-inflammatories, and antipyretics (fever reducers).

Codeine belongs to the group of medications called narcotic analgesics.

Caffeine belongs to the group of medications called stimulants.

ASA - caffeine - codeine is used for the relief of mild-to-severe pain, fever, and inflammation. It may be used to treat conditions such as headaches, pain due to cold symptoms, toothache, pain of menstrual cramps, arthritis pain, and the pain caused by muscle strains and sprains.

This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.

Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

What form(s) does this medication come in?

282 is no longer being manufactured for sale in Canada and is no longer available under any brand names. This article is being kept available for reference purposes only. If you are using this medication, speak with your doctor or pharmacist for information about your treatment options.

How should I use this medication?

The recommended adult dose varies according to need, but it is usually 1 or 2 tablets taken one to three times daily (every 4 to 8 hours) as required. No more than 4g of ASA (10 tablets) should be taken in any 24-hour period.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

This medication may be habit-forming if taken for long periods of time. It has the potential to be abused and should be taken only as needed for pain unless otherwise directed by your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If your doctor has told you to take this medication on a regular basis and you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

Who should NOT take this medication?

Do not use this medication if you:

  • are allergic or sensitive to ASA, codeine, caffeine, or any ingredients of the medication
  • are in the last three months of pregnancy or are nursing
  • are taking blood thinners such as warfarin
  • are 18 years of age or under
  • have a history of blood clotting problems
  • have a history of breathing problems after taking ASA or other anti-inflammatory medications
  • have an allergy or sensitivity to other anti-inflammatory medications
  • are experiencing respiratory depression
  • have severe anemia
  • have stomach ulcers or duodenal ulcers

What side effects are possible with this medication?

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

  • abdominal pain (mild)
  • constipation
  • diarrhea
  • dizziness
  • drowsiness
  • headache
  • heartburn
  • nausea
  • trouble sleeping
  • vomiting

Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

  • blurred or double-vision or other changes in vision
  • confusion
  • difficulty hearing
  • false sense of well-being
  • feeling faint
  • increased sweating
  • increased thirst
  • pounding, rapid heartbeat
  • redness or flushing of face
  • ringing or buzzing in the ears
  • signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
  • signs of decreased kidney function (e.g., difficulty or pain urinating, frequent urge to urinate, decrease in amount of urine)
  • signs of liver problems (e.g., nausea, vomiting, diarrhea, loss of appetite, weight loss, yellowing of the skin or whites of the eyes, dark urine, pale stools)
  • signs of unusual bleeding (e.g., bloody or black, tarry stools; vomiting of blood or material that looks like coffee grounds; unusual bruising or bleeding; nosebleeds)
  • skin rash, hives, or itching
  • trembling or uncontrolled muscle movements
  • unusual infections (symptoms may include fever or chills, severe diarrhea, shortness of breath, prolonged dizziness, headache, stiff neck, weight loss, or listlessness)

Stop taking the medication and seek immediate medical attention if any of the following occur:

  • signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
  • signs of breathing problems such as shallow, irregular breathing, or slow or troubled breathing
  • symptoms of overdose of codeine, such as:
    • abnormally slow or weak breathing
    • cold, clammy skin
    • confusion
    • extreme drowsiness
    • severe dizziness
    • slow heartbeat

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

Are there any other precautions or warnings for this medication?

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

HEALTH CANADA ADVISORY

June 8, 2021

Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.

A previous advisory on ASA - caffeine - codeine - butalbital was issued on July 31, 2020.

Abdominal conditions: Codeine may make the diagnosis of abdominal conditions more difficult or it may worsen these conditions. If you have an abdominal condition such as inflammatory or obstructive bowel disease, acute cholecystitis, or pancreatitis, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Bleeding disorders: ASA may increase bruising and bleeding from cuts that may take longer to stop. If you have a bleeding disorder or a history of bleeding problems, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Breathing: Codeine can suppress breathing. If you are at risk for breathing difficulties, such as asthma, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Constipation: Codeine can be very constipating. Eating a high-fibre diet and following good bowel habits will help to minimize this effect. If you develop constipation easily, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Dependence and withdrawal: This medication contains codeine. Physical dependence, psychological dependence, and abuse have occurred with the use of codeine. People with a history of past or current substance use problems may be at greater risk of developing abuse or addiction while taking this medication. Abuse is not a problem with people who require this medication for pain relief.

If you suddenly stop taking this medication, you may experience withdrawal symptoms such as anxiety, sweating, trouble sleeping, shaking, pain, nausea, tremors, diarrhea, and hallucinations. If you have been taking this medication for a while, it should be stopped gradually as directed by your doctor.

Drowsiness/reduced alertness: This medication may cause drowsiness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.

Gout: ASA may cause or worsen attacks of gout. Symptoms of an acute gout attack include sudden pain, swelling, and stiffness in the affected joint, often the big toe. You may also experience a fever. If this is your first attack, seek medical attention as soon as possible. If you have had gout attacks before, follow your doctor's instructions for dealing with the attack.

Head injury: If you have a head injury or increased pressure in the head, you may have a higher risk of experiencing side effects (breathing problems) or worsening of your condition while taking this medication. Discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Kidney function: Taking ASA - caffeine - codeine over a long period of time may increase the risk of developing kidney disease. If you have kidney disease or reduced kidney function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Liver function: If you have liver disease or reduced liver function, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Other medical conditions: If you are about to undergo surgery of the biliary tract, taking codeine may worsen your condition. It will also worsen the effects of acute alcohol intoxication and delirium tremens.

As well, if you have low thyroid (hypothyroidism), Addison's disease, benign prostatic hypertrophy (enlarged prostate), gallbladder disease, urethral stricture, decreased function of the adrenal glands, or porphyria, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

Stomach problems: ASA may cause stomach problems such as ulcers or bleeding. If you have a stomach problem, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. Call your doctor immediately if you notice signs such as stomach or abdominal pain, black tarry stools, or vomiting blood. Using ASA at the same time as other anti-inflammatory medications increases the risk of stomach ulcers and bleeding.

Surgery: ASA may cause increased bleeding during surgery. Do not take ASA - caffeine - codeine for 5 to 7 days before any surgery, including dental surgery, unless otherwise directed by your doctor or dentist. If you are scheduled for surgery, let your doctor know that you are taking this medication.

Pregnancy: This medication is not recommended for use by pregnant women unless the anticipated benefits outweigh the possible risks.

ASA taken near the end of pregnancy increases the risk of bleeding during delivery. Regular use of codeine by pregnant women may cause withdrawal symptoms in the newborn.

Breast-feeding: This medication passes into breast milk. Some of the codeine dose is converted into morphine by the body, once it has been taken. For some people, this change happens much faster than for others. If this happens to a nursing mother, the baby is a risk of receiving a morphine overdose through the breast milk.

If you are a breast-feeding mother and are taking ASA - caffeine - codeine, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The use of ASA may be associated with the development of Reye's syndrome in children and teenagers who have illnesses accompanied by fever, especially influenza and chickenpox. ASA should not be given to, or used by, children or teenagers who have chickenpox or flu symptoms unless a doctor is consulted.

Children are especially susceptible to an overdose of caffeine and its side effects on the central nervous system. ASA is one of the most frequent causes of accidental poisoning in toddlers and infants. Medications that contain ASA should be kept out of the reach of all children. This medication is not recommended for children less than 12 years of age.

Non-prescription products containing codeine should not be used by people under 18 years old. Recent evidence shows that young people who use opioids, including codeine, may be more likely to have problems with the misuse of medications and other substances later in life.

Seniors: Seniors may be at greater risk of side effects from this medication.

What other drugs could interact with this medication?

<

There may be an interaction between ASA - caffeine - codeine and any of the following:

  • abiraterone
  • acetazolamide
  • aclidinium
  • alcohol
  • alendronate
  • amphetamines (e.g., dextroamphetamine, lisdexamfetamine)
  • anesthetics
  • angiotensin converting enzyme inhibitors (ACEIs; e.g., captopril, ramipril)
  • antihistamines (e.g,. cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)
  • antipsychotics (e.g., chlorpromazine, clozapine, haloperidol, olanzapine, quetiapine, risperidone)
  • apixaban
  • atomoxetine
  • atropine
  • azelastine
  • barbiturates (e.g., butalbital, pentobarbital, phenobarbital)
  • belladonna
  • benzodiazepines (e.g., alprazolam, diazepam, lorazepam)
  • benztropine
  • brimonidine
  • buprenorphine
  • buspirone
  • butorphanol
  • calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
  • celecoxib
  • chloral hydrate
  • chloroquine
  • cilostazol
  • clopidogrel
  • oral corticosteroids (e.g., dexamethasone, hydrocortisone, prednisone)
  • cyclobenzaprine
  • dasatinib
  • decongestant cold medications (e.g., phenylephrine, pseudoephedrine)
  • decongestant eye drops and nose sprays (e.g., naphazoline, oxymetazoline, xylometazoline)
  • deferasirox
  • delaviridine
  • diabetes medications (e.g., chlorpropamide, glipizide, glyburide, insulin, metformin, nateglinide, rosiglitazone)
  • dipivefrin
  • dipyridamole
  • disopyramide
  • disulfiram
  • diuretics (water pills; e.g., furosemide, hydrochlorothiazide, triamterene)
  • dobutamine
  • dopamine
  • dronabinol
  • efavirenz
  • epinephrine
  • ethinyl estradiol
  • fast-acting bronchodilators (e.g., salbutamol, terbutaline)
  • flavoxate
  • gemfibrozil
  • general anesthetics (medications used to put people to sleep before surgery)
  • glucosamine
  • glycopyrrolate
  • herbal products that affect blood clotting (e.g., cat's claw, chamomile, fenugreek, evening primrose, feverfew, garlic, ginger, ginseng, turmeric)
  • imatinib
  • influenza vaccine
  • ipratropium
  • isoniazid
  • ketoconazole
  • ketotifen
  • linezolid
  • lithium
  • long-acting bronchodilators (e.g., formoterol, salmeterol)
  • lopinavir
  • low-molecular-weight heparins (e.g., dalteparin, enoxaparin, tinzaparin)
  • magnesium sulphate
  • methotrexate
  • methylphenidate
  • minocycline
  • mirabegron
  • mirtazapine
  • multivitamin/mineral supplements
  • muscle relaxants (e.g., baclofen, cyclobenzaprine, methocarbamol, orphenadrine)
  • nabilone
  • naltrexone
  • nilotinib
  • non-steroidal anti-inflammatory medications (NSAIDs; e.g., diclofenac, ibuprofen, naproxen)
  • norepinephrine
  • octreotide
  • olopatadine
  • omega-3 fatty acids
  • orphenadrine
  • other narcotic pain relievers (e.g., fentanyl, morphine, oxycodone)
  • oxybutynin
  • peginterferon alfa-2b
  • pegvisomant
  • pentazocine
  • perampanel
  • pramipexole
  • primaquine
  • probenecid
  • quinidine
  • quinine
  • quinolone antibiotics (e.g., ciprofloxacin, norfloxacin, ofloxacin)
  • ritonavir
  • rivaroxaban
  • ropinirole
  • rotigotine
  • rufinamide
  • scopolamine
  • seizure medications (e.g., clobazam, ethosuximide, felbamate, levetiracetam, phenobarbital, phenytoin, primidone, topiramate, valproic acid, zonisamide)
  • selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, fluoxetine, paroxetine, sertraline)
  • serotonin-norepinephrine reuptake inhibitors (SNRIs; desvenlafaxine, duloxetine, venlafaxine)
  • tapentadol
  • teriflunomide
  • theophyllines (e.g., aminophylline, oxtriphylline, theophylline)
  • ticagrelor
  • ticlopidine
  • tiotropium
  • tipranivir
  • tizanidine
  • thalidomide
  • tolterodine
  • tramadol
  • tranylcypromine
  • tricyclic antidepressants (e.g., amitriptyline, clomipramine, desipramine, trimipramine)
  • varicella virus vaccines
  • vitamin E
  • warfarin
  • zolpidem
  • zopiclone

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circ*mstances, your doctor may want you to:

  • stop taking one of the medications,
  • change one of the medications to another,
  • change how you are taking one or both of the medications, or
  • leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

All material copyright MediResource Inc. 1996 – 2024. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/282

282 - Uses, Side Effects, Interactions - MedBroadcast.com (2024)

FAQs

What is a muscle relaxer pill with 282 on it? ›

Pill with imprint IG 282 is Beige, Round and has been identified as Cyclobenzaprine Hydrochloride 5 mg. It is supplied by InvaGen Pharmaceuticals, Inc. Cyclobenzaprine is used in the treatment of Back Pain; Sciatica; Muscle Spasm; Pain and belongs to the drug class skeletal muscle relaxants.

What does cyclobenzaprine do to your body? ›

Descriptions. Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles.

What is a white pill with W 282 on it? ›

Pill with imprint W282 is White, Round and has been identified as Methylphenidate Hydrochloride 10 mg. It is supplied by Accord Healthcare Inc. Methylphenidate is used in the treatment of ADHD; Narcolepsy; Depression and belongs to the drug class CNS stimulants. Risk cannot be ruled out during pregnancy.

Is 10 mg of cyclobenzaprine a narcotic? ›

Official answer. No, cyclobenzaprine is not classified as a controlled substance by the DEA and does not have physically addictive or abuse properties like an opioid or benzodiazepine. It is not a narcotic drug.

Is Cyclobenzaprine Hydrochloride the same as Xanax? ›

Xanax is mainly used to treat anxiety disorders and panic attacks. Brand names for cyclobenzaprine include Flexeril, Amrix, and Fexmid. Cyclobenzaprine and Xanax belong to different drug classes. Cyclobenzaprine is a muscle relaxant and Valium is a benzodiazepine.

What are 3 drug interactions? ›

There are three types of drug interactions: Drug-drug interaction: A reaction between two (or more) drugs. Drug-food interaction: A reaction between a drug and a food or beverage. Drug-condition interaction: A reaction that occurs when taking a drug while having a certain medical condition.

What medications cannot be taken with muscle relaxers? ›

Possible cyclobenzaprine interactions include alcohol, opioids such as tramadol (Conzip, Qdolo), and benzodiazepines such as alprazolam (Xanax). It can also interact with medications that increase serotonin levels, including several antidepressants, migraine medications like sumatriptan (Imitrex), and St. John's wort.

How many hours does 10 mg of cyclobenzaprine last? ›

Studies in healthy adults suggest that a lower dose may produce less sedation. Because cyclobenzaprine's duration of action is 4 to 6 hours, reducing the dosing frequency to 10 mg BID would create a potentially painful untreated interval between doses.

Is cyclobenzaprine hard on your heart? ›

These cardiac-related issues have been reported to occur in less than 1% of people taking the 10 mg dose in clinical trials. Older adults may be more at risk for heart rhythm changes. People ages 65 years and older generally shouldn't start cyclobenzaprine at a dose higher than 5 mg.

What is 282 prescription drug? ›

This combination product contains acetylsalicylic acid (ASA), caffeine, codeine, and meprobamate. Codeine and ASA are pain relievers, while meprobamate is a muscle relaxant. Caffeine is added to enhance the pain-relieving effects of the medication.

What pill is L 282? ›

Pill with imprint L282 is White, Capsule/Oblong and has been identified as Clemastine Fumarate 1.34 mg.

What kind of pill is cyclobenzaprine? ›

Cyclobenzaprine hydrochloride is approved for use in the United States as a muscle relaxant. It is marketed under the brand names Flexeril® and Amrix® and as generic formulations in 5, 7.5, and 10 mg tablets intended for short-term (2 to 3 week) oral administration. The usual starting dose is 5 mg, three times per day.

Does muscle relaxer methocarbamol make you sleepy? ›

This medicine may cause some people to become dizzy or drowsy. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert. Make sure any doctor or dentist who treats you knows that you are using this medicine.

Is cyclobenzaprine a good muscle relaxer? ›

Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem.

Which is better muscle relaxer methocarbamol or cyclobenzaprine? ›

Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 607 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Methocarbamol has an average rating of 6.3 out of 10 from a total of 293 ratings on Drugs.com.

What is a muscle relaxer called methocarbamol? ›

Methocarbamol is a centrally-acting skeletal muscle relaxant (SMR) approved for the treatment of acute musculoskeletal pain. Specific FDA indications for use are vague and have not been recently reviewed. Methocarbamol has been approved for muscle spasms since 1957.

Top Articles
Latest Posts
Article information

Author: Carmelo Roob

Last Updated:

Views: 5389

Rating: 4.4 / 5 (65 voted)

Reviews: 80% of readers found this page helpful

Author information

Name: Carmelo Roob

Birthday: 1995-01-09

Address: Apt. 915 481 Sipes Cliff, New Gonzalobury, CO 80176

Phone: +6773780339780

Job: Sales Executive

Hobby: Gaming, Jogging, Rugby, Video gaming, Handball, Ice skating, Web surfing

Introduction: My name is Carmelo Roob, I am a modern, handsome, delightful, comfortable, attractive, vast, good person who loves writing and wants to share my knowledge and understanding with you.